Adhesion of Pancreatic Cancer Cells in a Liver-Microvasculature Mimicking Coculture Correlates with Their Propensity to Form Liver-Specific Metastasis In Vivo

Adhesion of Pancreatic Cancer Cells in a Liver-Microvasculature Mimicking Coculture Correlates with Their Propensity to Form Liver-Specific Metastasis In Vivo

Organ-specific characteristic of endothelial cells (ECs) is crucial for specific adhesion of cancer cells to ECs, which is a key factor in the formation of organ-specific metastasis. In this study, we developed a coculture of TMNK-1 (immortalized liver sinusoidal ECs) with 10T1/2 (resembling hepatic...

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Bibliographic Details
Main Authors: Chowdhury, Mohammad Mahfuz, Danoy, Mathieu, Rahman, Farhana, Shinohara, Marie, Kaneda, Shohei, Shiba, Kiyotaka, Fujita, Naoya, Fujii, Teruo, Sakai, Yasuyuki
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037581/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037581/

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