Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes

We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune...

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Main Authors: Parra, Gabriel I., Green, Kim Y.
Format: Online
Language:English
Published: Centers for Disease Control and Prevention 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036768/
id pubmed-4036768
recordtype oai_dc
spelling pubmed-40367682014-06-04 Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes Parra, Gabriel I. Green, Kim Y. Dispatch We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design. Centers for Disease Control and Prevention 2014-06 /pmc/articles/PMC4036768/ /pubmed/24857806 http://dx.doi.org/10.3201/eid2006.131627 Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Parra, Gabriel I.
Green, Kim Y.
spellingShingle Parra, Gabriel I.
Green, Kim Y.
Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
author_facet Parra, Gabriel I.
Green, Kim Y.
author_sort Parra, Gabriel I.
title Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_short Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_full Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_fullStr Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_full_unstemmed Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_sort sequential gastroenteritis episodes caused by 2 norovirus genotypes
description We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.
publisher Centers for Disease Control and Prevention
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036768/
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