Interactions between permeation and gating in the TMEM16B/anoctamin2 calcium-activated chloride channel

Extracellular anions more permeant than Cl− modulate TMEM16B gating to promote channel opening, whereas less permeant anions favor channel closure.

Bibliographic Details
Main Authors: Betto, Giulia, Cherian, O. Lijo, Pifferi, Simone, Cenedese, Valentina, Boccaccio, Anna, Menini, Anna
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035747/