Malignant Melanoma with Concurrent BRAF E586K and NRAS Q81K Mutations

Cutaneous melanoma is an aggressive malignant tumor of melanocytes which accounts for 80% of skin cancer-related deaths. A number of driver mutations have been identified in melanoma, with the mutually exclusive BRAF V600E and NRAS Q61A mutations together accounting for roughly 70% of mutations. Sim...

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Bibliographic Details
Main Authors: Shackelford, Rodney, Pollen, Maressa, Vora, Moise, Jusion, Tamara T., Cotelingam, James, Nair, Binu
Format: Online
Language:English
Published: S. Karger AG 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035678/