Role of Leukotrienes and Leukotriene Modifiers in Asthma

Leukotrienes (LTs), including cysteinyl LTs (CysLTs) and LTB4, are potent lipid mediators that are pivotal in the pathophysiology of asthma phenotypes. At least two receptor subtypes for CysLTs – CysLT1 and CysLT2 – have been identified. Most of the pathophysiological effects of CysLTs in asthma, in...

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Bibliographic Details
Main Author: Montuschi, Paolo
Format: Online
Language:English
Published: MDPI 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033953/