Gαi2- and Gαi3-Deficient Mice Display Opposite Severity of Myocardial Ischemia Reperfusion Injury

G-protein-coupled receptors (GPCRs) are the most abundant receptors in the heart and therefore are common targets for cardiovascular therapeutics. The activated GPCRs transduce their signals via heterotrimeric G-proteins. The four major families of G-proteins identified so far are specified through...

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Bibliographic Details
Main Authors: Köhler, David, Devanathan, Vasudharani, Bernardo de Oliveira Franz, Claudia, Eldh, Therese, Novakovic, Ana, Roth, Judith M., Granja, Tiago, Birnbaumer, Lutz, Rosenberger, Peter, Beer-Hammer, Sandra, Nürnberg, Bernd
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032280/