Population Pharmacokinetic Study of Benznidazole in Pediatric Chagas Disease Suggests Efficacy despite Lower Plasma Concentrations than in Adults

Population Pharmacokinetic Study of Benznidazole in Pediatric Chagas Disease Suggests Efficacy despite Lower Plasma Concentrations than in Adults

Chagas disease is a parasitic disease endemic to the Americas. Long term complications include severe cardiac involvement, which can lead to severe disability and death of affected individuals. Treatment options for Chagas disease are limited to 2 drugs (benznidazole and nifurtimox), but knowledge o...

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Bibliographic Details
Main Authors: Altcheh, Jaime, Moscatelli, Guillermo, Mastrantonio, Guido, Moroni, Samanta, Giglio, Norberto, Marson, Maria Elena, Ballering, Griselda, Bisio, Margarita, Koren, Gideon, García-Bournissen, Facundo
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031103/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031103/

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