Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells

Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells

Ring chromosomes are structural aberrations commonly associated with birth defects, mental disabilities, and growth retardation1,2. Rings form upon fusion of the long and short arms of a chromosome, sometimes associated with large terminal deletions2. Due to the severity of these large-scale aberrat...

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Bibliographic Details
Main Authors: Bershteyn, Marina, Hayashi, Yohei, Desachy, Guillaume, Hsiao, Edward C., Sami, Salma, Tsang, Kathryn M., Weiss, Lauren A., Kriegstein, Arnold R., Yamanaka, Shinya, Wynshaw-Boris, Anthony
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030630/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030630/

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