Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction

Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction

Recent genetic studies have linked mental illness to alterations in disrupted in schizophrenia 1 (DISC1), a multifunctional scaffolding protein that regulates cyclic adenosine monophosphate (cAMP) signaling via interactions with phosphodiesterase 4 (PDE4). High levels of cAMP during stress exposure...

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Bibliographic Details
Main Authors: Gamo, N J, Duque, A, Paspalas, C D, Kata, A, Fine, R, Boven, L, Bryan, C, Lo, T, Anighoro, K, Bermudez, L, Peng, K, Annor, A, Raja, A, Mansson, E, Taylor, S R, Patel, K, Simen, A A, Arnsten, A F T
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030323/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030323/

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