Epidermal Growth Factor Receptor Inhibition Slows Progression of Diabetic Nephropathy in Association With a Decrease in Endoplasmic Reticulum Stress and an Increase in Autophagy
Previous studies by us and others have reported renal epidermal growth factor receptors (EGFRs) are activated in models of diabetic nephropathy. In the present study, we examined the effect of treatment with erlotinib, an inhibitor of EGFR tyrosine kinase activity, on the progression of diabetic nep...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Diabetes Association
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030104/ |