Intranasal H5N1 Vaccines, Adjuvanted with Chitosan Derivatives, Protect Ferrets against Highly Pathogenic Influenza Intranasal and Intratracheal Challenge

Intranasal H5N1 Vaccines, Adjuvanted with Chitosan Derivatives, Protect Ferrets against Highly Pathogenic Influenza Intranasal and Intratracheal Challenge

We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian Influenza (HPAI) intratracheal and intranasal challenge in a ferret model.

Bibliographic Details
Main Authors: Mann, Alex J., Noulin, Nicolas, Catchpole, Andrew, Stittelaar, Koert J., de Waal, Leon, Veldhuis Kroeze, Edwin J. B., Hinchcliffe, Michael, Smith, Alan, Montomoli, Emanuele, Piccirella, Simona, Osterhaus, Albert D. M. E., Knight, Alastair, Oxford, John S., Lapini, Giulia, Cox, Rebecca, Lambkin-Williams, Rob
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029577/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029577/

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