Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system

Kidney disease is a public health problem that affects more than 20 million people in the US adult population, yet little is understood about the impact of kidney disease on drug disposition. Consequently there is a critical need to be able to model the human kidney and other organ systems, to impro...

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Bibliographic Details
Main Authors: Kelly, Edward J, Wang, Zhican, Voellinger, Jenna L, Yeung, Cathy K, Shen, Danny D, Thummel, Kenneth E, Zheng, Ying, Ligresti, Giovanni, Eaton, David L, Muczynski, Kimberly A, Duffield, Jeremy S, Neumann, Thomas, Tourovskaia, Anna, Fauver, Mark, Kramer, Greg, Asp, Elizabeth, Himmelfarb, Jonathan
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029535/