Anti-Cancer Potential of MAPK Pathway Inhibition in Paragangliomas–Effect of Different Statins on Mouse Pheochromocytoma Cells

Anti-Cancer Potential of MAPK Pathway Inhibition in Paragangliomas–Effect of Different Statins on Mouse Pheochromocytoma Cells

To date, malignant pheochromocytomas and paragangliomas (PHEOs/PGLs) cannot be effectively cured and thus novel treatment strategies are urgently needed. Lovastatin has been shown to effectively induce apoptosis in mouse PHEO cells (MPC) and the more aggressive mouse tumor tissue-derived cells (MTT)...

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Bibliographic Details
Main Authors: Fliedner, Stephanie M. J., Engel, Tobias, Lendvai, Nikoletta K., Shankavaram, Uma, Nölting, Svenja, Wesley, Robert, Elkahloun, Abdel G., Ungefroren, Hendrik, Oldoerp, Angela, Lampert, Gary, Lehnert, Hendrik, Timmers, Henri, Pacak, Karel
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028222/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028222/

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