Congenic Mapping and Allele-Specific Alteration Analysis of Stmm1 Locus Conferring Resistance to Early-Stage Chemically Induced Skin Papillomas

Genome-wide association studies have revealed that many low-penetrance cancer susceptibility loci are located throughout the genome; however, a very limited number of genes have been identified so far. Using a forward genetics approach to map such loci in a mouse skin cancer model, we previously ide...

Full description

Bibliographic Details
Main Authors: Okumura, Kazuhiro, Saito, Megumi, Isogai, Eriko, Miura, Ikuo, Wakana, Shigeharu, Kominami, Ryo, Wakabayashi, Yuichi
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028187/