Predictive Simulation Approach for Designing Cancer Therapeutic Regimens with Novel Biological Mechanisms

Introduction Ursolic acid (UA) is a pentacyclic triterpene acid present in many plants, including apples, basil, cranberries, and rosemary. UA suppresses proliferation and induces apoptosis in a variety of tumor cells via inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells (...

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Bibliographic Details
Main Authors: Doudican, Nicole A., Mazumder, Amitabha, Kapoor, Shweta, Sultana, Zeba, Kumar, Ansu, Talawdekar, Anay, Basu, Kabya, Agrawal, Ashish, Aggarwal, Aditi, Shetty, Krithika, Singh, Neeraj K, Kumar, Chandan, Tyagi, Anuj, Singh, Neeraj Kumar, Darlybai, Janitha C, Abbasi, Taher, Vali, Shireen
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026994/