Oral Vaccination with Heat Inactivated Mycobacterium bovis Activates the Complement System to Protect against Tuberculosis

Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model for mycobacterial infection and TB to characterize the pr...

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Bibliographic Details
Main Authors: Beltrán-Beck, Beatriz, de la Fuente, José, Garrido, Joseba M., Aranaz, Alicia, Sevilla, Iker, Villar, Margarita, Boadella, Mariana, Galindo, Ruth C., Pérez de la Lastra, José M., Moreno-Cid, Juan A., Fernández de Mera, Isabel G., Alberdi, Pilar, Santos, Gracia, Ballesteros, Cristina, Lyashchenko, Konstantin P., Minguijón, Esmeralda, Romero, Beatriz, de Juan, Lucía, Domínguez, Lucas, Juste, Ramón, Gortazar, Christian
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026474/