Impact of Genetic Background on Neonatal Lethality of Gga2 Gene-Trap Mice

The functional redundancy of the three mammalian Golgi-localized, γ-ear–containing, ADP-ribosylation factor-binding proteins (GGAs) was addressed in a previous study. Using insertional mutagenesis, we found that Gga1 or Gga3 homozygous knockout mice were for the most part normal, whereas mice homozy...

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Bibliographic Details
Main Authors: Doray, Balraj, Govero, Jennifer, Kornfeld, Stuart
Format: Online
Language:English
Published: Genetics Society of America 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025487/