A recombinant fusion protein containing a spider toxin specific for the insect voltage-gated sodium ion channel shows oral toxicity towards insects of different orders

Recombinant fusion protein technology allows specific insecticidal protein and peptide toxins to display activity in orally-delivered biopesticides. The spider venom peptide δ-amaurobitoxin-PI1a, which targets insect voltage-gated sodium channels, was fused to the “carrier” snowdrop lectin (GNA) to...

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Bibliographic Details
Main Authors: Yang, Sheng, Pyati, Prashant, Fitches, Elaine, Gatehouse, John A.
Format: Online
Language:English
Published: Elsevier Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024200/