DNA Replication Is an Integral Part of the Mouse Oocyte’s Reprogramming Machinery

Many of the structural and mechanistic requirements of oocyte-mediated nuclear reprogramming remain elusive. Previous accounts that transcriptional reprogramming of somatic nuclei in mouse zygotes may be complete in 24–36 hours, far more rapidly than in other reprogramming systems, raise the questio...

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Bibliographic Details
Main Authors: Wang, Bingyuan, Pfeiffer, Martin J., Schwarzer, Caroline, Araúzo-Bravo, Marcos J., Boiani, Michele
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023938/