Immune checkpoints: A therapeutic target in triple negative breast cancer

Early clinical trials investigating monoclonal antibodies targeting the T-cell inhibitory receptor programmed cell death 1 (PD-1) and its ligand PD-L1 have shown efficacy in melanoma, non-small cell lung cancer and renal cell carcinoma. We recently demonstrated PD-L1 expression in 20% of triple nega...

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Bibliographic Details
Main Authors: Chawla, Akhil, Philips, Anne V, Alatrash, Gheath, Mittendorf, Elizabeth
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022604/