eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency

Mutations in the CETP gene resulting in defective CETP activity have been shown to cause remarkable elevations of plasma HDL-C levels, with the accumulation in plasma of large, buoyant HDL particles enriched in apolipoprotein E. Genetic CETP deficiency thus represents a unique tool to evaluate how s...

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Bibliographic Details
Main Authors: Gomaraschi, Monica, Ossoli, Alice, Pozzi, Silvia, Nilsson, Peter, Cefalù, Angelo B., Averna, Maurizio, Kuivenhoven, Jan Albert, Hovingh, G. Kees, Veglia, Fabrizio, Franceschini, Guido, Calabresi, Laura
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022511/