Selective Depletion of Regulatory T Cell Subsets by Docetaxel Treatment in Patients with Nonsmall Cell Lung Cancer

Regulatory T (Treg) cells are potent suppressors that maintain immune homeostasis. Accumulation of Treg can inhibit effective immune responses in cancer patients, leading to tumor development and progression. Despite direct cytotoxicity, several chemotherapeutic drugs have been reported to deplete T...

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Bibliographic Details
Main Authors: Li, Jie-Yao, Duan, Xiu-Fang, Wang, Li-Ping, Xu, Yu-Jie, Huang, Lan, Zhang, Teng-Fei, Liu, Jin-Yan, Li, Feng, Zhang, Zhen, Yue, Dong-Li, Wang, Fei, Zhang, Bin, Zhang, Yi
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020463/