Selective Depletion of Regulatory T Cell Subsets by Docetaxel Treatment in Patients with Nonsmall Cell Lung Cancer
Regulatory T (Treg) cells are potent suppressors that maintain immune homeostasis. Accumulation of Treg can inhibit effective immune responses in cancer patients, leading to tumor development and progression. Despite direct cytotoxicity, several chemotherapeutic drugs have been reported to deplete T...
Main Authors: | , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020463/ |