Roles of gap junctions, connexins, and pannexins in epilepsy

Enhanced gap junctional communication (GJC) between neurons is considered a major factor underlying the neuronal synchrony driving seizure activity. In addition, the hippocampal sharp wave ripple complexes, associated with learning and seizures, are diminished by GJC blocking agents. Although gap ju...

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Bibliographic Details
Main Authors: Mylvaganam, Shanthini, Ramani, Meera, Krawczyk, Michal, Carlen, Peter L.
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019879/