Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements

We studied the time course of serum insulin level in a patient who injected large amounts of regular insulin in an attempted suicide. A 58‐year‐old woman attempted suicide by subcutaneously injecting herself with 2400 U regular insulin. On arrival, the serum glucose level was 2.4 mmol/L (44 mg/dL) a...

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Main Authors: Hiromine, Yoshihisa, Kawabata, Yumiko, Yamauchi, Takaaki, Noso, Shinsuke, Babaya, Naru, Harada, Takeshi, Ito, Hiroyuki, Ikegami, Hiroshi
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019248/
id pubmed-4019248
recordtype oai_dc
spelling pubmed-40192482014-05-19 Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements Hiromine, Yoshihisa Kawabata, Yumiko Yamauchi, Takaaki Noso, Shinsuke Babaya, Naru Harada, Takeshi Ito, Hiroyuki Ikegami, Hiroshi Articles We studied the time course of serum insulin level in a patient who injected large amounts of regular insulin in an attempted suicide. A 58‐year‐old woman attempted suicide by subcutaneously injecting herself with 2400 U regular insulin. On arrival, the serum glucose level was 2.4 mmol/L (44 mg/dL) and the serum insulin level was 40,000 pmol/L (5700 μIU/mL). The serum insulin level was high, with a maximum of 110,000 pmol/L (16,000 μIU/mL) at 13 h after injection, followed by an initial rapid decrease and a subsequent slow decrease, with hyperinsulinemia lasting as long as 5 days after injection. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2012.00211.x, 2012) Blackwell Publishing Ltd 2012-03-27 2012-10-18 /pmc/articles/PMC4019248/ /pubmed/24843608 http://dx.doi.org/10.1111/j.2040-1124.2012.00211.x Text en © 2012 Asian Association for the Study of Diabetes and Wiley Publishing Asia Pty Ltd
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Hiromine, Yoshihisa
Kawabata, Yumiko
Yamauchi, Takaaki
Noso, Shinsuke
Babaya, Naru
Harada, Takeshi
Ito, Hiroyuki
Ikegami, Hiroshi
spellingShingle Hiromine, Yoshihisa
Kawabata, Yumiko
Yamauchi, Takaaki
Noso, Shinsuke
Babaya, Naru
Harada, Takeshi
Ito, Hiroyuki
Ikegami, Hiroshi
Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements
author_facet Hiromine, Yoshihisa
Kawabata, Yumiko
Yamauchi, Takaaki
Noso, Shinsuke
Babaya, Naru
Harada, Takeshi
Ito, Hiroyuki
Ikegami, Hiroshi
author_sort Hiromine, Yoshihisa
title Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements
title_short Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements
title_full Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements
title_fullStr Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements
title_full_unstemmed Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements
title_sort prolonged hyperinsulinemia after subcutaneous injection of 2400 u regular insulin in a suicide attempt: time course of serum insulin with frequent measurements
description We studied the time course of serum insulin level in a patient who injected large amounts of regular insulin in an attempted suicide. A 58‐year‐old woman attempted suicide by subcutaneously injecting herself with 2400 U regular insulin. On arrival, the serum glucose level was 2.4 mmol/L (44 mg/dL) and the serum insulin level was 40,000 pmol/L (5700 μIU/mL). The serum insulin level was high, with a maximum of 110,000 pmol/L (16,000 μIU/mL) at 13 h after injection, followed by an initial rapid decrease and a subsequent slow decrease, with hyperinsulinemia lasting as long as 5 days after injection. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2012.00211.x, 2012)
publisher Blackwell Publishing Ltd
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019248/
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