Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Wen-Dan Decoction (WDD), a formula of traditional Chinese medicine, has been clinically used for treating insomnia for approximately 800 years. However, the therapeutic mechanisms of WDD remain unclear. Orexin-A plays a key role in the sleep-wake cycle, while leptin function is opposite to orexin-A....

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Bibliographic Details
Main Authors: Wu, Fengzhi, Song, Yuehan, Li, Feng, He, Xin, Ma, Jie, Feng, Ting, Guan, Binghe, Wang, Liye, Li, Sinai, Liu, Xiaolan, Liu, Yan, Mao, Meng, Liu, Jing, Bai, Shijing, Song, Cai
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016855/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016855/

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