Lipid Profiling and Transcriptomic Analysis Reveals a Functional Interplay between Estradiol and Growth Hormone in Liver

17β-estradiol (E2) may interfere with endocrine, metabolic, and gender-differentiated functions in liver in both females and males. Indirect mechanisms play a crucial role because of the E2 influence on the pituitary GH secretion and the GHR-JAK2-STAT5 signaling pathway in the target tissues. E2, th...

Full description

Bibliographic Details
Main Authors: Fernández-Pérez, Leandro, Santana-Farré, Ruymán, de Mirecki-Garrido, Mercedes, García, Irma, Guerra, Borja, Mateo-Díaz, Carlos, Iglesias-Gato, Diego, Díaz-Chico, Juan Carlos, Flores-Morales, Amilcar, Díaz, Mario
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015979/