Estrogen increases haematopoietic stem cell self-renewal in females and during pregnancy

Sexually dimorphic mammalian tissues, including sexual organs and the brain, contain stem cells that are directly or indirectly regulated by sex hormones1-6. An important question is whether stem cells also exhibit sex differences in physiological function and hormonal regulation in tissues that do...

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Bibliographic Details
Main Authors: Nakada, Daisuke, Oguro, Hideyuki, Levi, Boaz P., Ryan, Nicole, Kitano, Ayumi, Saitoh, Yusuke, Takeichi, Makiko, Wendt, George R., Morrison, Sean J.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015622/