GLP‐1 receptor agonist attenuates endoplasmic reticulum stress‐mediated β‐cell damage in Akita mice

GLP‐1 receptor agonist attenuates endoplasmic reticulum stress‐mediated β‐cell damage in Akita mice

Aims/Introduction:  Endoplasmic reticulum (ER) stress is one of the contributing factors in the development of type 2 diabetes. To investigate the cytoprotective effect of glucagon‐like peptide 1 receptor (GLP‐1R) signaling in vivo, we examined the action of exendin‐4 (Ex‐4), a potent GLP‐1R agonist...

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Bibliographic Details
Main Authors: Yamane, Shunsuke, Hamamoto, Yoshiyuki, Harashima, Shin‐ichi, Harada, Norio, Hamasaki, Akihiro, Toyoda, Kentaro, Fujita, Kazuyo, Joo, Erina, Seino, Yutaka, Inagaki, Nobuya
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015545/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015545/

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