Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse
Background: Quantitative estimation of toxicokinetic variability in the human population is a persistent challenge in risk assessment of environmental chemicals. Traditionally, interindividual differences in the population are accounted for by default assumptions or, in rare cases, are based on huma...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
NLM-Export
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014769/ |