Low and high linear energy transfer radiation sensitization of HCC cells by metformin

The purpose of this study was to investigate the efficacy of metformin as a radiosensitizer for use in combination therapy for human hepatocellular carcinoma (HCC). Three human HCC cell lines (Huh7, HepG2, Hep3B) and a normal human hepatocyte cell line were treated with metformin alone or with radia...

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Bibliographic Details
Main Authors: KIM, Eun Ho, Kim, Mi-Sook, Cho, Chul-Koo, Jung, Won-Gyun, Jeong, Youn Kyoung, Jeong, Jae-Hoon
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014154/