Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations

The cloaca is temporally formed and eventually divided by the urorectal septum (URS) during urogenital and anorectal organ development. Although congenital malformations, such as anorectal malformations (ARMs), are frequently observed during this process, the underlying pathogenic mechanisms remain...

Full description

Bibliographic Details
Main Authors: Miyagawa, S, Harada, M, Matsumaru, D, Tanaka, K, Inoue, C, Nakahara, C, Haraguchi, R, Matsushita, S, Suzuki, K, Nakagata, N, Ng, R C-L, Akita, K, Lui, V C-H, Yamada, G
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013517/