MLL1/WDR5 complex in leukemogenesis and epigenetic regulation
MLL1 is a histone H3Lys4 methyltransferase and forms a complex with WDR5 and other components. It plays important roles in developmental events, transcriptional regulation, and leukemogenesis. MLL1 -fusion proteins resulting from chromosomal translocations are molecular hallmarks of a special type o...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Sun Yat-sen University Cancer Center
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013350/ |