Knockdown of nucleophosmin induces S-phase arrest in HepG2 cells

Nucleophosmin/B23 (NPM) is a universally expressed nucleolar phosphoprotein that participates in proliferation, apoptosis, ribosome assembly, and centrosome duplication; however, the role of NPM in cell cycle regulation is not well characterized. We investigated the mechanism by which NPM is involve...

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Bibliographic Details
Main Authors: Wang, Qing-Qing, Zhang, Zhi-Yi, Xiao, Jian-Yong, Yi, Chun, Li, Lin-Zi, Huang, Yan, Yun, Jing-Ping
Format: Online
Language:English
Published: Sun Yat-sen University Cancer Center 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013333/