Potential of vesicular stomatitis virus as an oncolytic therapy for recurrent and drug-resistant ovarian cancer

In the last decade, we have gained significant understanding of the mechanism by which vesicular stomatitis virus (VSV) specifically kills cancer cells. Dysregulation of translation and defective innate immunity are both thought to contribute to VSV oncolysis. Safety and efficacy are important objec...

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Bibliographic Details
Main Authors: Heiber, Joshua F., Xu, Xiang-Xi, Barber, Glen N.
Format: Online
Language:English
Published: Sun Yat-sen University Cancer Center 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013328/