Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells

Balance between pro-tumor and anti-tumor effects may be affected by molecular interactions within tumor microenvironment. On this basis we searched for molecular partners of ADAMTS-12, a secreted metalloprotease that shows both oncogenic and tumor-suppressive effects. Using its spacer region as a ba...

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Bibliographic Details
Main Authors: Fontanil, Tania, Rúa, Susana, Llamazares, María, Moncada-Pazos, Angela, Quirós, Pedro M., García-Suórez, Olivia, Vega, Jose A., Sasaki, Takako, Mohamedi, Yamina, Esteban, Manuel M., Obaya, Alvaro J., Cal, Santiago
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012729/