Wiskott–Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans☆

Wiskott–Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans☆

Wiskott–Aldrich Syndrome protein (WASp) regulates the cytoskeleton in hematopoietic cells and mutations in its gene cause the Wiskott–Aldrich Syndrome (WAS), a primary immunodeficiency with microthrombocytopenia, eczema and a higher susceptibility to develop tumors. Autoimmune manifestations, freque...

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Bibliographic Details
Main Authors: Castiello, Maria Carmina, Bosticardo, Marita, Pala, Francesca, Catucci, Marco, Chamberlain, Nicolas, van Zelm, Menno C., Driessen, Gertjan J., Pac, Malgorzata, Bernatowska, Ewa, Scaramuzza, Samantha, Aiuti, Alessandro, Sauer, Aisha V., Traggiai, Elisabetta, Meffre, Eric, Villa, Anna, van der Burg, Mirjam
Format: Online
Language:English
Published: Academic Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012141/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012141/

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