Reduced Gamma Oscillations in a Mouse Model of Intellectual Disability: A Role for Impaired Repetitive Neurotransmission?

Intellectual disability affects 2–3% of the population; mutations of the X-chromosome are a major cause of moderate to severe cases. The link between the molecular consequences of the mutation and impaired cognitive function remains unclear. Loss of function mutations of oligophrenin-1 (OPHN1) disru...

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Bibliographic Details
Main Authors: Powell, Andrew D., Saintot, Pierre-Philippe, Gill, Kalbinder K., Bharathan, Ashtami, Buck, S. Caroline, Morris, Gareth, Jiruska, Premysl, Jefferys, John G. R.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011727/