Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

Experimental autoimmune uveoretinitis is a model for noninfectious posterior segment intraocular inflammation in humans. Although this disease is CD4+ T cell dependent, in the persistent phase of disease CD8+ T cells accumulate. We show that these are effector memory CD8+ T cells that differ from th...

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Bibliographic Details
Main Authors: Boldison, Joanne, Chu, Colin J., Copland, David A., Lait, Philippa J. P., Khera, Tarnjit K., Dick, Andrew D., Nicholson, Lindsay B.
Format: Online
Language:English
Published: AAI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009498/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009498/

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