Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibitor of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression

Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibitor of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression

Computational techniques, and in particular molecular dynamics (MD) simulations, have been successfully used as a complementary technique to predict and analyse the structural behaviour of nucleic acids, including peptide nucleic acid- (PNA-) RNA hybrids. This study shows that a 7-base long PNA comp...

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Bibliographic Details
Main Authors: Amato, Felice, Tomaiuolo, Rossella, Nici, Fabrizia, Borbone, Nicola, Elce, Ausilia, Catalanotti, Bruno, D'Errico, Stefano, Morgillo, Carmine Marco, De Rosa, Giuseppe, Mayol, Laura, Piccialli, Gennaro, Oliviero, Giorgia, Castaldo, Giuseppe
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009323/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009323/

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