Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study

Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study

The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase (IDO), thereby stimulating tryptophan degradation along the kynurenine pathway. Pl...

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Bibliographic Details
Main Authors: Apalset, E M, Gjesdal, C G, Ueland, P M, Midttun, Ø, Ulvik, A, Eide, G E, Meyer, K, Tell, G S
Format: Online
Language:English
Published: John Wiley & Sons Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008990/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008990/

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