Transcriptome Profiling of Human Ulcerative Colitis Mucosa Reveals Altered Expression of Pathways Enriched in Genetic Susceptibility Loci

Human colonic mucosa altered by inflammation due to ulcerative colitis (UC) displays a drastically altered pattern of gene expression compared with healthy tissue. We aimed to understand the underlying molecular pathways influencing these differences by analyzing three publically-available, independ...

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Bibliographic Details
Main Authors: Cardinale, Christopher J., Wei, Zhi, Li, Jin, Zhu, Junfei, Gu, Mengnan, Baldassano, Robert N., Grant, Struan F. A., Hakonarson, Hakon
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006814/