Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches☆

Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches☆

•E. coli cyclic-AMP receptor protein (CRP) is a paradigm of gene regulation.•Comparison of CRPs reveals differences in their affinity of cAMP.•A range of dependency on cAMP for DNA-binding exists.•CRPs have adapted to function in the specific niches occupied by the bacteria.

Bibliographic Details
Main Authors: Green, Jeffrey, Stapleton, Melanie R, Smith, Laura J, Artymiuk, Peter J, Kahramanoglou, Christina, Hunt, Debbie M, Buxton, Roger S
Format: Online
Language:English
Published: Current Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005916/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005916/

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