CD28 and ITK signals regulate autoreactive T cell trafficking

CD28 and ITK signals regulate autoreactive T cell trafficking

Activation of self-reactive T cells and their trafficking to target tissues leads to autoimmune organ destruction. Mice lacking the coinhibitory receptor CTLA-4 develop fatal autoimmunity characterized by massive lymphocytic invasion into non-lymphoid tissues. Here we demonstrate that the CD28 costi...

Full description

Bibliographic Details
Main Authors: Jain, Nitya, Miu, Bing, Jiang, Jian-kang, McKinstry, Kai K., Prince, Amanda, Swain, Susan L, Greiner, Dale L., Thomas, Craig J., Sanderson, Michael J., Berg, Leslie J, Kang, Joonsoo
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005518/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005518/

Similar Items