Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer

Activation of numerous pathways has been documented in non-small cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) has emerged as a common therapeutic target. The mitogen-activated protein kinase (MAPK) and AKT signaling pathways are downstream of EGFR and deregulated via genetic and...

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Bibliographic Details
Main Authors: Kitano, Haruhisa, Chung, Joon-Yong, Ylaya, Kris, Conway, Catherine, Takikita, Mikiko, Fukuoka, Junya, Doki, Yoshinori, Hanaoka, Jun, Hewitt, Stephen M.
Format: Online
Language:English
Published: SAGE Publications 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005365/