Surface modified multifunctional nanomedicines for simultaneous imaging and therapy of cancer
Introduction: To date, a growing number of advanced anticancer nanomedicines (e.g., Doxil®, Lipoxal®, DepoCyte®) have entered into different phases of clinical trials. However, most of these medicaments fail to differentiate between diseased and normal cells. They also do not have capability of rea...
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| Format: | Online |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005281/ |
| Summary: | Introduction: To date, a growing number of advanced anticancer nanomedicines (e.g., Doxil®, Lipoxal®, DepoCyte®) have entered into different phases of clinical trials. However, most of these medicaments fail to differentiate between diseased and normal cells. They also do not have capability of real time monitoring of disease status trough on-demand imaging/sensing of target molecule(s). Multifunctional nanomedicines and theranostics can resolve such limitations, while formulation of these advanced seamless systems appear to involve various sophisticated process, exploiting several bioconjugations.
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