Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus
The fat body in invertebrates was shown to participate in energy storage and homeostasis, apart from its other roles in immune mediation and protein synthesis to mention a few. Thus, sharing similar characteristics with the liver and adipose tissues in vertebrates. However, vertebrate adipose tissue...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005007/ |
| id |
pubmed-4005007 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-40050072014-05-01 Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus Azeez, Odunayo Ibraheem Meintjes, Roy Chamunorwa, Joseph Panashe Review The fat body in invertebrates was shown to participate in energy storage and homeostasis, apart from its other roles in immune mediation and protein synthesis to mention a few. Thus, sharing similar characteristics with the liver and adipose tissues in vertebrates. However, vertebrate adipose tissue or fat has been incriminated in the pathophysiology of metabolic disorders due to its role in production of pro-inflammatory cytokines. This has not been reported in the insect fat body. The link between the fat body and adipose tissue was examined in this review with the aim of determining the principal factors responsible for resistance to inflammation in the insect fat body. This could be the missing link in the prevention of metabolic disorders in vertebrates, occasioned by obesity. BioMed Central 2014-04-23 /pmc/articles/PMC4005007/ /pubmed/24758278 http://dx.doi.org/10.1186/1476-511X-13-71 Text en Copyright © 2014 Azeez et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Azeez, Odunayo Ibraheem Meintjes, Roy Chamunorwa, Joseph Panashe |
| spellingShingle |
Azeez, Odunayo Ibraheem Meintjes, Roy Chamunorwa, Joseph Panashe Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| author_facet |
Azeez, Odunayo Ibraheem Meintjes, Roy Chamunorwa, Joseph Panashe |
| author_sort |
Azeez, Odunayo Ibraheem |
| title |
Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| title_short |
Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| title_full |
Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| title_fullStr |
Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| title_full_unstemmed |
Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| title_sort |
fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus |
| description |
The fat body in invertebrates was shown to participate in energy storage and homeostasis, apart from its other roles in immune mediation and protein synthesis to mention a few. Thus, sharing similar characteristics with the liver and adipose tissues in vertebrates. However, vertebrate adipose tissue or fat has been incriminated in the pathophysiology of metabolic disorders due to its role in production of pro-inflammatory cytokines. This has not been reported in the insect fat body. The link between the fat body and adipose tissue was examined in this review with the aim of determining the principal factors responsible for resistance to inflammation in the insect fat body. This could be the missing link in the prevention of metabolic disorders in vertebrates, occasioned by obesity. |
| publisher |
BioMed Central |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005007/ |
| _version_ |
1612083770627719168 |