Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer

Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer

Lung cancer evades host immune surveillance by dysregulating inflammation. Tumors and their surrounding stromata produce growth factors, cytokines, and chemokines that recruit, expand, and/or activate myeloid-derived suppressor cells (MDSCs). MDSCs regulate immune responses and are frequently found...

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Bibliographic Details
Main Authors: Srivastava, Minu K, Zhu, Li, Harris-White, Marni, Huang, Min, St John, Maie, Lee, Jay M, Salgia, Ravi, Cameron, Robert B, Strieter, Robert, Dubinett, Steven, Sharma, Sherven
Format: Online
Language:English
Published: Dove Medical Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004632/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004632/

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