Adenylyl cyclase 4 does not regulate collecting duct water and sodium handling

Adenylyl cyclase (AC)‐stimulated cAMP is a key mediator of collecting duct (CD) Na and water transport. AC isoforms 3, 4, and 6 are expressed in the CD. Our group demonstrated that AC6, but not AC3, is involved in regulating CD Na and water transport. However, the role of AC4 in such regulation rema...

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Bibliographic Details
Main Authors: Kittikulsuth, Wararat, Stuart, Deborah, Kohan, Donald E.
Format: Online
Language:English
Published: Wiley Periodicals, Inc. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002255/