Dichotomous mechanisms of aortic stiffening in high‐fat diet fed young and old B6D2F1 mice

Advancing age is associated with increased stiffness of large elastic arteries as assessed by aortic pulse wave velocity (PWV). Greater PWV, associated with increased risk of cardiovascular diseases, may result from altered expression of the extracellular matrix proteins, collagen and elastin, as we...

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Bibliographic Details
Main Authors: Henson, Grant D., Walker, Ashley E., Reihl, Kelly D., Donato, Anthony J., Lesniewski, Lisa A.
Format: Online
Language:English
Published: Wiley Periodicals, Inc. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002248/