Conformational Dynamics of DNA G-Quadruplex in Solution Studied by Kinetic Capillary Electrophoresis Coupled On-line with Mass Spectrometry**
G-quadruplex-forming DNA/RNA sequences play an important role in the regulation of biological functions and development of new anticancer and anti-aging drugs. In this work, we couple on-line kinetic capillary electrophoresis with mass spectrometry (KCE-MS) to study conformational dynamics of DNA G-...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Wiley-VCH Verlag GmbH & Co
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000168/ |